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5-HTP

Nutritional Support For:
• Sleeplessness
• Anxiety
• Mild Depression
• Obsessive Compulsive Disorder

5-hydroxytryptophan (5-HTP) is the less well known cousin of serotonin (5-HT), one of the most important brain neurotransmitters. Tryptophan is first converted to 5-HTP in nerve cells by a vitamin B3 dependant enzyme, and then 5-HTP is converted to 5-HT by a vitamin B6 dependant enzyme. Yet thanks to modern science, we can now take preformed 5-HTP, with many consequent advantages.

5-HTP passes through the blood brain barrier into the brain far more easily than tryptophan, and getting tryptophan through the blood brain barrier is the main bottleneck, which in many people leads to inadequate brain serotonin levels. Also, 5-HTP is not used to make proteins in the body, while tryptophan is, so there isn’t competition by cells outside the brain for 5-HTP, as there is for the body’s scarce tryptophan supplies. The body often uses tryptophan to make vitamin B3, at a very high cost of 60mg tryptophan to make just 1mg B3!  5-HTP is not wasted to make vitamin B3.



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